If you’re thinking about dissolving your filler, here’s what you need to know before booking your appointment.
Dermal fillers are a popular way to enhance facial features, smooth wrinkles, and restore lost volume—but what happens if you change your mind about the results? Whether your filler migrated, feels lumpy, or just no longer suits your aesthetic, you don’t have to live with it. Enter Hylenex, an enzyme-based injectable that dissolves hyaluronic acid (HA) fillers safely and effectively.
What Is Hylenex?
Hylenex (also called hyaluronidase) is an enzyme that breaks down hyaluronic acid, the main ingredient in most popular dermal fillers like JUVÉDERM®, Restylane®, and Belotero®. When injected into the area where filler is present, Hylenex starts working almost immediately to dissolve the product. It’s a precise and customizable treatment that allows trained providers to selectively reduce or completely eliminate unwanted filler.
It’s important to note: Hylenex only works on HA-based fillers. If you’ve been treated with a non-HA filler like Radiesse® or Sculptra®, Hylenex will not be effective.

Why People Choose to Dissolve Filler
There are plenty of valid reasons to consider dissolving your filler. Common concerns include:
- Overfilled or unnatural appearance
- Filler migration (when the product spreads to unintended areas)
- Asymmetry or lumpiness
- Changes in aesthetic preference
- Long-term buildup after repeated treatments
- Medical necessity (e.g., vascular complications or allergic reactions)
Dissolving your filler doesn’t mean you’ve made a mistake; it means you’re prioritizing your appearance and skin health.
What to Expect During the Process
The dissolving process at TKI is relatively quick and straightforward:
- Consultation: Your TKI provider will assess your concerns, review your treatment history, and determine whether Hylenex is right for you.
- Patch Test (if needed): For patients with allergies or sensitivities, a patch test may be done to rule out a reaction.
- Treatment: A small amount of Hylenex is injected directly into the filler-treated area. You may feel a slight sting, but the procedure is typically well tolerated.
- Results: You may begin to see softening or breakdown of the filler within minutes, though complete results usually appear within 24–72 hours. Some areas or denser fillers may require multiple sessions.
Mild swelling, bruising, or tenderness can occur after treatment, but these side effects generally resolve quickly.
Will My Natural Features Be Affected?
One common worry is that Hylenex might dissolve your body’s natural hyaluronic acid, but the good news is that your body quickly replenishes its natural stores. Our skilled injectors use targeted placement and conservative dosing to ensure that only the unwanted filler is dissolved while preserving your natural facial structure.
What’s Next After Dissolving?
After dissolving your filler and once the area has healed, you have options. You can choose to:
- Leave the area natural
- Try a different filler with a more subtle effect
- Re-treat with better technique or product placement
At TKI, we often work with patients who want a “filler refresh.” Our team carefully maps your facial anatomy and goals to achieve a balanced, natural-looking outcome, whether that means re-filling or simply resetting.
Start Fresh with Confidence
If you’re no longer happy with your dermal filler results, dissolving your filler is a proactive and empowering choice. At TKI, our experienced providers offer safe, precise Hylenex treatments and personalized guidance on what comes next. Whether you want to start over or simplify your aesthetic, we’re here to help you love what you see in the mirror.
Ready to hit reset? Schedule a consultation at TKI today by filling out the form below or call/text (855) 537-5242 / 8-555-DRKAGA to request an appointment. Let’s get you back to feeling confident in your skin.